VERBASCOSIDE: Lippia citriodora extract

Lippia citriodora  background

fig.1 - Lippia citriodora
commonly known as Lemon Verbena or Lemon beebrush

Lippia citriodora or Lemon Verbena is synonymous with Aloysia triphylla, Verbena citriodora and Verbena triphyilla (fig.1).
Plants of genus Lippia were and are still generally used by indigenous populations of South America and by the traditional Chinese medicine for the treatment of respiratory diseases such as cold and flu, cough and bronchitis.

Additionally, L. citriodora leaves are used as seasoning for food preparations or flavoring for beverages.

Lippia is used in medicine as a relaxant and carminative herb that counteracts stress related conditions, especially those that affect the stomach.
Other medical uses regard the treatment of dyspepsia, headaches, neuralgic pain and vertigo. From cell culture of Lippia citriodora, ABR extracts the ingredient VERBASCOSIDE.

Verbascoside (known also as Acteoside) is a secondary metabolite produced by the plant as defense against insects and parasites.

Verbascoside is a phenylpropanoid widely distributed in the plant kingdom and its structure is characterized by a caffeic acid and a hydroxytyrosol residues bound to a glucopyranoside at its opposite sides through an ester and a glycosidic bond respectively (fig.2).

ACTEOS 10P - the product

fig. 2 - Chemical structure of Verbascoside

ACTEOS 10P is the ABR commercial name of the active ingredient Verbascoside titrated at 10%, extracted and purified from Lippia citriodora suspension cell culture.
ACTEOS 10P is a Novel Food authorized ingredient.

Verbascoside - biological effects

Scientific literature attributes to Verbascoside various biological properties including anti-hepatotoxic, antinflammatory, anti-nociceptive, antioxidant and antihemolytic effects.

Verbascoside also demonstrated relevant effects in the reduction of symptoms in chronic pathologies and conditions such as:

  • Arthritis
  • Hypertension
  • Parkinson’s disease
  • Alzheimer’s disease
  • Estrogenic mediated diseases
  • Allergy type 1
  • Intestinal mucosytis

Scientific literature, preclinical and clinical data are freely available at ABR Reserved Area upon on-line registration.

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Manufactured under licensed technology from IRB S.p.A. – Altavilla Vicentina